Publication history
Role of the hypothetical protein BB0563 during Borrelia burgdorferi infection in animals. Christina Thompson, Connor Waldron, Sierra George, and Zhiming Ouyang. Infection and Immunity. 06 Feb 2023. Read here
BB0761, a MepM homolog, contributes to Borrelia burgdorferi cell division and mammalian infectivity. Christina Thompson, Sierra George, Maria L. White, Prahathees J. Eswara, Zhiming Ouyang. Molecular Microbiology. 05 May 2022. Read here
The Lon-1 protease is required by Borrelia burgdorferi to infect the mammalian host. Christina Thompson, Charlotte Mason, Shidoya Parilla, Zhiming Ouyang. Infection and Immunity. 20 May 2020. Read here
DksA plays an essential role in regulating the virulence of Borrelia burgdorferi. Charlotte Mason, Christina Thompson, Zhiming Ouyang. Molecular Microbiology. 30 Mar 2020. Read here
The Lon-2 protease of Borrelia burgdorferi is critical for infection in the mammalian host. Charlotte Mason, Christina Thompson, Zhiming Ouyang. Molecular Microbiology. 18 Jan 2020. Read Here
The CXXC motifs are essential for the function of BosR in Borrelia burgdorferi. Charlotte Mason, Xiaoyan Liu, Spoorthy Prabhudeva, Zhiming Ouyang. Frontiers in Cellular and Infection Microbiology. 16 Apr 2019. Read here
Mandraju R, Jain A, Gao Y, Ouyang Z, Norgard MV, Pasare C. MyD88 Signaling in T Cells Is Critical for Effector CD4 T Cell Differentiation following a Transitional T Follicular Helper Cell Stage. Infection and immunity. 86(5) , 2018. http://www.ncbi.nlm.nih.gov/pubmed/29507085
Ouyang Z, Zhou J. The putative Walker A and Walker B motifs of Rrp2 are required for the growth of Borrelia burgdorferi. Molecular microbiology. 103(1) : 86-98, 2017. http://www.ncbi.nlm.nih.gov/pubmed/27696536
Ouyang Z, Zhou J, Norgard MV. Evidence that BosR (BB0647) Is a Positive Autoregulator in Borrelia burgdorferi. Infection and immunity. 84(9) : 2566-74, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27324485
Ouyang Z, Zhou J. BadR (BB0693) controls growth phase-dependent induction of rpoS and bosR in Borrelia burgdorferi via recognizing TAAAATAT motifs. Molecular microbiology. 98(6) : 1147-67, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26331438
Ouyang Z, Zhou J, Norgard MV. CsrA (BB0184) is not involved in activation of the RpoN-RpoS regulatory pathway in Borrelia burgdorferi. Infection and immunity. 82(4) : 1511-22, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24452681
Brautigam CA, Ouyang Z, Deka RK, Norgard MV. Sequence, biophysical, and structural analyses of the PstS lipoprotein (BB0215) from Borrelia burgdorferi reveal a likely binding component of an ABC-type phosphate transporter. Protein science : a publication of the Protein Society. 23(2) : 200-12, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24318969
Ouyang Z, Zhou J, Norgard MV. Synthesis of RpoS is dependent on a putative enhancer binding protein Rrp2 in Borrelia burgdorferi. PloS one. 9(5) : e96917, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24810170
Ouyang Z, Zhou J, Brautigam CA, Deka R, Norgard MV. Identification of a core sequence for the binding of BosR to the rpoS promoter region in Borrelia burgdorferi. Microbiology (Reading, England). 160(Pt 5) : 851-62, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24608174
Brautigam CA, Deka RK, Ouyang Z, Machius M, Knutsen G, Tomchick DR, Norgard MV. Biophysical and bioinformatic analyses implicate the Treponema pallidum Tp34 lipoprotein (Tp0971) in transition metal homeostasis. Journal of bacteriology. 194(24) : 6771-81, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23042995
Ouyang Z, Narasimhan S, Neelakanta G, Kumar M, Pal U, Fikrig E, Norgard MV. Activation of the RpoN-RpoS regulatory pathway during the enzootic life cycle of Borrelia burgdorferi. BMC microbiology. 12: 44, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22443136
He M, Ouyang Z, Troxell B, Xu H, Moh A, Piesman J, Norgard MV, Gomelsky M, Yang XF. Cyclic di-GMP is essential for the survival of the lyme disease spirochete in ticks. PLoS pathogens. 7(6) : e1002133, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21738477
Ouyang Z, Deka RK, Norgard MV. BosR (BB0647) controls the RpoN-RpoS regulatory pathway and virulence expression in Borrelia burgdorferi by a novel DNA-binding mechanism. PLoS pathogens. 7(2) : e1001272, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21347346
Ouyang Z, Haq S, Norgard MV. Analysis of the dbpBA upstream regulatory region controlled by RpoS in Borrelia burgdorferi. Journal of bacteriology. 192(7) : 1965-74, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20118265
Ouyang Z, Kumar M, Kariu T, Haq S, Goldberg M, Pal U, Norgard MV. BosR (BB0647) governs virulence expression in Borrelia burgdorferi. Molecular microbiology. 74(6) : 1331-43, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19889086
Ouyang Z, He M, Oman T, Yang XF, Norgard MV. A manganese transporter, BB0219 (BmtA), is required for virulence by the Lyme disease spirochete, Borrelia burgdorferi. Proceedings of the National Academy of Sciences of the United States of America. 106(9) : 3449-54, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19218460
Boardman BK, He M, Ouyang Z, Xu H, Pang X, Yang XF. Essential role of the response regulator Rrp2 in the infectious cycle of Borrelia burgdorferi. Infection and immunity. 76(9) : 3844-53, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18573895
Ouyang Z, Blevins JS, Norgard MV. Transcriptional interplay among the regulators Rrp2, RpoN and RpoS in Borrelia burgdorferi. Microbiology (Reading, England). 154(Pt 9) : 2641-58, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18757798
Ouyang Z, Isaacson R. Identification of a Novel Regulator for the Escherichia coli fit Iron Transport System. The open microbiology journal. 2: 94-9, 2008. http://www.ncbi.nlm.nih.gov/pubmed/19088918
Ouyang Z, Isaacson R. Identification and characterization of a novel ABC iron transport system, fit, in Escherichia coli. Infection and immunity. 74(12) : 6949-56, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16982838