Publication history

  • Role of the hypothetical protein BB0563 during Borrelia burgdorferi infection in animals. Christina Thompson, Connor Waldron, Sierra George, and Zhiming Ouyang. Infection and Immunity. 06 Feb 2023. Read here

  • BB0761, a MepM homolog, contributes to Borrelia burgdorferi cell division and mammalian infectivity. Christina Thompson, Sierra George, Maria L. White, Prahathees J. Eswara, Zhiming Ouyang. Molecular Microbiology. 05 May 2022. Read here

  • The Lon-1 protease is required by Borrelia burgdorferi to infect the mammalian host. Christina Thompson, Charlotte Mason, Shidoya Parilla, Zhiming Ouyang. Infection and Immunity. 20 May 2020. Read here

  • DksA plays an essential role in regulating the virulence of Borrelia burgdorferi. Charlotte Mason, Christina Thompson, Zhiming Ouyang. Molecular Microbiology. 30 Mar 2020. Read here

  • The Lon-2 protease of Borrelia burgdorferi is critical for infection in the mammalian host. Charlotte Mason, Christina Thompson, Zhiming Ouyang. Molecular Microbiology. 18 Jan 2020. Read Here

  • The CXXC motifs are essential for the function of BosR in Borrelia burgdorferi. Charlotte Mason, Xiaoyan Liu, Spoorthy Prabhudeva, Zhiming Ouyang. Frontiers in Cellular and Infection Microbiology. 16 Apr 2019. Read here

  • Mandraju R, Jain A, Gao Y, Ouyang Z, Norgard MV, Pasare C. MyD88 Signaling in T Cells Is Critical for Effector CD4 T Cell Differentiation following a Transitional T Follicular Helper Cell Stage. Infection and immunity. 86(5) , 2018. http://www.ncbi.nlm.nih.gov/pubmed/29507085

  • Ouyang Z, Zhou J. The putative Walker A and Walker B motifs of Rrp2 are required for the growth of Borrelia burgdorferi. Molecular microbiology. 103(1) : 86-98, 2017. http://www.ncbi.nlm.nih.gov/pubmed/27696536

  • Ouyang Z, Zhou J, Norgard MV. Evidence that BosR (BB0647) Is a Positive Autoregulator in Borrelia burgdorferi. Infection and immunity. 84(9) : 2566-74, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27324485

  • Ouyang Z, Zhou J. BadR (BB0693) controls growth phase-dependent induction of rpoS and bosR in Borrelia burgdorferi via recognizing TAAAATAT motifs. Molecular microbiology. 98(6) : 1147-67, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26331438

  • Ouyang Z, Zhou J, Norgard MV. CsrA (BB0184) is not involved in activation of the RpoN-RpoS regulatory pathway in Borrelia burgdorferi. Infection and immunity. 82(4) : 1511-22, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24452681

  • Brautigam CA, Ouyang Z, Deka RK, Norgard MV. Sequence, biophysical, and structural analyses of the PstS lipoprotein (BB0215) from Borrelia burgdorferi reveal a likely binding component of an ABC-type phosphate transporter. Protein science : a publication of the Protein Society. 23(2) : 200-12, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24318969

  • Ouyang Z, Zhou J, Norgard MV. Synthesis of RpoS is dependent on a putative enhancer binding protein Rrp2 in Borrelia burgdorferi. PloS one. 9(5) : e96917, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24810170

  • Ouyang Z, Zhou J, Brautigam CA, Deka R, Norgard MV. Identification of a core sequence for the binding of BosR to the rpoS promoter region in Borrelia burgdorferi. Microbiology (Reading, England). 160(Pt 5) : 851-62, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24608174

  • Brautigam CA, Deka RK, Ouyang Z, Machius M, Knutsen G, Tomchick DR, Norgard MV. Biophysical and bioinformatic analyses implicate the Treponema pallidum Tp34 lipoprotein (Tp0971) in transition metal homeostasis. Journal of bacteriology. 194(24) : 6771-81, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23042995

  • Ouyang Z, Narasimhan S, Neelakanta G, Kumar M, Pal U, Fikrig E, Norgard MV. Activation of the RpoN-RpoS regulatory pathway during the enzootic life cycle of Borrelia burgdorferi. BMC microbiology. 12: 44, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22443136

  • He M, Ouyang Z, Troxell B, Xu H, Moh A, Piesman J, Norgard MV, Gomelsky M, Yang XF. Cyclic di-GMP is essential for the survival of the lyme disease spirochete in ticks. PLoS pathogens. 7(6) : e1002133, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21738477

  • Ouyang Z, Deka RK, Norgard MV. BosR (BB0647) controls the RpoN-RpoS regulatory pathway and virulence expression in Borrelia burgdorferi by a novel DNA-binding mechanism. PLoS pathogens. 7(2) : e1001272, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21347346

  • Ouyang Z, Haq S, Norgard MV. Analysis of the dbpBA upstream regulatory region controlled by RpoS in Borrelia burgdorferi. Journal of bacteriology. 192(7) : 1965-74, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20118265

  • Ouyang Z, Kumar M, Kariu T, Haq S, Goldberg M, Pal U, Norgard MV. BosR (BB0647) governs virulence expression in Borrelia burgdorferi. Molecular microbiology. 74(6) : 1331-43, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19889086

  • Ouyang Z, He M, Oman T, Yang XF, Norgard MV. A manganese transporter, BB0219 (BmtA), is required for virulence by the Lyme disease spirochete, Borrelia burgdorferi. Proceedings of the National Academy of Sciences of the United States of America. 106(9) : 3449-54, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19218460

  • Boardman BK, He M, Ouyang Z, Xu H, Pang X, Yang XF. Essential role of the response regulator Rrp2 in the infectious cycle of Borrelia burgdorferi. Infection and immunity. 76(9) : 3844-53, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18573895

  • Ouyang Z, Blevins JS, Norgard MV. Transcriptional interplay among the regulators Rrp2, RpoN and RpoS in Borrelia burgdorferi. Microbiology (Reading, England). 154(Pt 9) : 2641-58, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18757798

  • Ouyang Z, Isaacson R. Identification of a Novel Regulator for the Escherichia coli fit Iron Transport System. The open microbiology journal. 2: 94-9, 2008. http://www.ncbi.nlm.nih.gov/pubmed/19088918

  • Ouyang Z, Isaacson R. Identification and characterization of a novel ABC iron transport system, fit, in Escherichia coli. Infection and immunity. 74(12) : 6949-56, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16982838